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Gut microbiota disruption has the potential to provoke a number of processes, including neuroinflammation, BBB dysfunction, dysregulation in immunity, and new patterns in neurotransmitter metabolism

However, cell viability was not decreased with the cotreatment of BSO and FG4592 (Supplemental Figure 8D), suggesting GSH depletion is not the major mechanism of cell death after DMF and FG4592 cotreatment

10.1016/j.cbpa.2016.01.023 42 MurphyM

Acta 1139 , 7783 (1992)