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Evidence suggests that metformin lowers vitamin B12 levels and raises homocysteine levels in patients with type 2 diabetes Observational studies have suggested that metformin causes vitamin B12 deficiency in some patients

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Commonly used for blood sugar management, Metformin can interfere with how the small intestine absorbs B12

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For example, one dark beer like a Guinness contains 4.3% alcohol by volume, whereas a dry martini contains anywhere from 37 to 42% alcohol