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(See also Overview of Inflammatory Bowel Disease (IBD).) Locating the Large Intestine (Colon) Ulcerative colitis usually starts in the rectum (ulcerative proctitis)
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doi: 10.1016/j.beem.2005.07.004
As far as I know (I'm not medically trained or a scientist) overdosing B12 is unlikely as excess passes out in urine
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