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CrossRef Tumor cell-derived IL-23 promotes hepatocellular carcinoma progression via an autocrine IL-23/EGFR/AKT signaling axis Xuan Zhou, Yongxian Chen, Jie Li, Yin Zhang, Jian Li, Yabin Guo Biochemical and Biophysical Research Communications .2026

The sequence and lengths of the polyglutamine (CAG) and polyglycine (GGC) repeats of the AR NTD are highly variable in the human population 22,23,24

Future research should focus on integrating multi-omics technologies to decipher the precise molecular regulatory network of the testicular-penile axis, validating novel biomarkers in large clinical cohorts, accelerating the translational research of novel targeted therapies, and establishing a comprehensive personalized management system based on immune-inflammatory status

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There is significant genetic heterogeneity in MAD deficiency with some genotype-phenotype correlations
