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Consequently, many AML subtypes display marked dependence on cystine uptake mediated by the system xc- (SLC7A11) antiporter, which imports extracellular cystine for subsequent reduction to cysteine and incorporation into glutathione for antioxidant defense [46,47]

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Oct 21 2020;21(20)doi:10.3390/ijms21207796

This clarifies the reason why there are not many reports regarding Bcc infections in Egypt and other nations 12

CHAC1 overexpression induces ER stress markers BIP and CHOP, and promotes ferroptosis by increasing lipid peroxides and reducing GPX4 levels

Hubli M, Dietz V, Bolliger M