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Furthermore, it is increasingly evident that excess abdominal fat is closely associated with the development of metabolic disturbances [5,6,7] while accumulation of fat in the lower body is associated with a protective glucose and lipid profile after adjustment for total body fat mass [8, 9]

The 12mg dose group achieved an average 24.2% body weight reduction over 48 weeks

A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps- 1 function

Three-dimensional image acquisition The samples were imaged with Zeiss LSM880 microscope, using a plan-Apochromat 63x/1.4 Oil DIC, and a 405-nm diode laser, 488 nm line of argon laser, 561-nm DPSS diode laser, 633-nm HeNe laser: with 70-nm xy pixel size, and 210-nm z -spacing

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