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In the outer nuclear layer (ONL), pathological changes manifested as edema and an increase in the space between the photoreceptor nuclei were noted

Neuron 89, 956970

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Put a longer, stronger push together with a lifted brake and a second push, and the combined pulse is meaningfully bigger than either lever moving alone

For instance, neurons have high energy demands, and mtDNA damage in the CNS contributes to HIV-associated neurocognitive disorders (HAND) through neuronal energy failure and neuroinflammation (9195)