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Clinical investigations have shown that melatonin concentrations in the CSF of patients with AD are several-fold lower than those in age-matched control subjects without AD [75, 229]
However, in CV injury models (TAA and CCl4), the production of liver progenitor-like cells was not observed (Li et al., 2019)
Basque J, Martel M, Leduc R, Cantin AM
doi: 10.3233/JAD-171020
In cell culture experiments, it exhibits similar effects to SAHA, as it has the capability to impede cancer cell growth and induce both DNA double-strand break damage and cell apoptosis simultaneously (Pojani and Barlocco, 2021)
