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Despite its name (which references the pineal gland), pinealon was derived from studies of cortexin, a brain cortex extract, and its primary documented effects are on neuronal function rather than pineal-specific activity

PPs could decrease AFs-associated oxidative stress, genotoxic, mutagenic, and carcinogenic effects by improving cellular antioxidant balance, regulation of signaling pathways, alleviating inflammatory responses, and modification of gene expression profile in a dose/time-reliant fashion

Cell 166, 167180

We propose that the GHK-Cu complex may act therapeutically against age-associated neurodegeneration and cognitive decline

These mechanisms are detailed in Figure 3A

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