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Description
This pathway is responsible for the calcium-dependent release of neuropeptides, neurotrophic factors, granins, neurohormones, and transmembrane proteins [33] (Table 1)
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a critical review
10.1079/WPS19850007 176
Further supporting this notion of the bidirectional relationship between age and sleep-wake disruption, studies have noted that behavioral or genetic manipulation of circadian rhythms also causes aging-like phenotypes (Hood and Amir, 2017)
Nelson DB, Tayob N, Mitchell KG, Correa AM, Hofstetter WL, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Antonoff MB, Roth JA, Rice DC , Mehran RJ
