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10 - 12 Lumithera developed the first multiwavelength PBM device to treat ocular indications, the Valeda Light Delivery System

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[2] Nitric Oxide System & Endothelial Research Research applications include studies of: Endothelial nitric oxide synthase (eNOS) modulation through upstream kinase pathways Caveolin-1 (Cav-1) binding interactions with eNOS in cell culture Nitric oxide (NO) production mechanisms and microcirculatory effects in vascular models Platelet aggregation pathways in coagulation research Studies examine NO production mechanisms following cav-1 displacement in endothelial cell models and microcirculatory perfusion in preclinical research systems

Apoptosis and cell cycle disturbances induced by coumarin and 7-hydroxycoumarin on human lung carcinoma cell lines