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It was first identified in human plasma in 1973 by biochemist Loren Pickart, who noticed that older liver tissue exposed to a protein fraction from young blood began behaving like young tissue

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Inhibition of the NRF2-GSH axis sensitizes the small molecule Ras-Selective Lethal 3 (RSL3) to induce ferroptosis in Kirsten Rat Sarcoma Viral Oncogene Homolog Lung Adenocarcinoma cells in vitro

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