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Furthermore, CD28 signals modulate glucose and fatty acid metabolism early after activation, coinciding with preservation of mitochondrial cristae flexibility and metabolic plasticity, which is crucial for the development of functional Tm cells capable of secondary immune responses (89, 166, 180)

Miss either element and the claim is incomplete

Literature indicates that nearly one-third of psychiatric and psychogeriatric hospital admissions exhibit low red cell folate levels or decreased serum folate levels, even in the absence of anemia or macrocytosis (, )

It has been shown in research settings to activate receptors linked to neuron growth and synapse formation

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