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Even though there is evidence that cuprizone could lead to excitotoxicity in oligodendrocytes and neurons, the precise impacts of cuprizone on NMDAR-mediated cell death are not fully understood but could provide a mechanism by which glutamate in the lesion can induce myelin damage (Fig

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Located within the conservation area of Sutton Courtenay, the house is elevated above the 1 in 100-year flood level, allowing for rising waters and future climate change impacts