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Assays performed with leaf extracts of these lines indicated that GSAAT(C138S) and GSAAT(C396) are weakly stimulated by the addition of DTT (by up to 20% compared to their UT samples)

Data availability All data are available within this article and its Supplementary information

The bioconversion of such new compounds, including but not limited to prodrugs, requires the participation of enzymes, such as esterase (Walther et al., 2017)

c Number of patients for which the time to first exacerbation is available

1), and approved by the local ethics committee

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