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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

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Luikenhuis S, Perrone G, Dawes IW, Grant CM (1998) The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species

Keywords: Mycobacterium tuberculosis , Tuberculosis, Infectious diseases, Host response, Host-directed therapy Introduction Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis ( M.tb ) and is the second leading cause of death from infectious diseases worldwide, following coronavirus disease 2019

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