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Linker chemistry plays a critical role, where disulfide (SS) or diselenide (SeSe) bonds connect the drug to the carrier, enabling selective cleavage under reducing conditions

A deficiency in glutathione may lead to increased susceptibility to oxidative stress, fatigue, weakened immune function, and potential skin problems, highlighting the importance of this antioxidant in overall health

The ethics committee of Alexandria University, Egypt, approved the design and the protocol of the experimental work according to the regulatory framework in ethics of animal research

- Diuretics: because it can inhibit their activity

10.1128/MCB.00441-17 Mol