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Assessment of NR4A ligands that directly bind and modulate the orphan nuclear receptor Nurr1

10.1002/mnfr.201800536 30 WuT.LiJ.LiY.SongH
Despite its lack of specificity, the innate immune system comprises a multitude of differentiated cell types that have evolved to protect the body from foreign invaders and have developed complex responses to pathogens, toxins, and allergens [23]

& Fan, W

GPX4-IN-17 GPX4 inhibitor 17 is a ferrocene-containing inhibitor of glutathione peroxidase 4 (GPX4) and an inducer of ferroptosis

In all, it appears that an ideal treatment would target thrombosis or platelet aggregation, without increasing the risk for bleeding
