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However, these mechanisms have not been proven in humans

J Drug Deliv Ther 13(9):4148

In our study, we systematically demonstrated that ACTL6A inhibited GC cell ferroptosis by promoting GSH synthesis through upregulating GCLC

This has been confirmed in experimental studies on NSCLC cell lines, including A549 and H1299, where treatment with rhamnetin resulted in elevated levels of cleaved caspase-3, caspase-9, and PARP [89, 101]

Egyptian Journal of Basic and Applied Sciences 10:460475
