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It is important to note that whilst B12 deficiency can cause nerve pain, not all nerve pain is caused by B12 deficiency

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Some medical conditions, including autoimmune disease like shingles (herpes zoster), rheumatoid arthritis or celiac disease, as well as Lyme disease, some cancers, and several other diseases can also cause or increase the risk of nerve damage, also sometimes referred to as peripheral neuropathy

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However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms