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Pregnant or breastfeeding women, due to a lack of safety data regarding copper absorption during pregnancy

175 Future research may help clarify whether the inconsistencies in findings from clinical trials are due to differences in vitamin D and calcium doses, baseline vitamin D levels, genetic factors affecting vitamin D receptors, or other factors affecting bone health

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Understanding this relationship is critical because your pharmacy might send you a different vial size than you expected, and you need to adjust your reconstitution volume to maintain your preferred concentration