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Senescent cells secrete the senescence-associated secretory phenotype (SASP), which consists of inflammatory cytokines and chemokine growth factors, into the surrounding tissues

Sapio MR, Iadarola MJ, LaPaglia DM, Lehky T, Thurm AE, Danley KM, Fuhr SR, Lee MD, Huey AE, Sharp SJ, Tsao JW, Yanovski JA, Mannes AJ, Han JC (2019) Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity
Its a way of fine-tuning your internal systems to help them perform at their best, which is a core principle of regenerative medicine
Insulin resistance: Growth hormone antagonizes insulin's effects

Lyophilized Material Appearance Lyophilized material may appear cracked, fragmented, chipped, or loose within the vial

Seiwerth, Sven et al
