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I experienced minor redness at injection sites during the first two weeks that went away on its own

Acknowledgments The authors thank Arnulf Koeppen for generously providing the FRDA heart pictures, Dr

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However, educated by environmental signals in the TME, macrophages can acquire a M2-like phenotype and transform into tumor-associated macrophages (TAMs), which are known to facilitate tumor progression 18,19,20

Taken together, the above considerations regarding the prevalence and clinical correlates of HT highlight this disease as an area of unmet medical need with broad relevance for public health