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Third, the RNAi effect was temporary, and off-target effects cannot be completely ruled out, although gene-specific fragments and the ds GFP control minimize this concern

10.1016/j.jsmc.2015.08.004 364 VinogradovaI

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It was later reported that this cinnamic derivative reduced hippocampal neuronal apoptosis and oxidative stress and protected PC-12 cells against the influx of Ca 2+ , malondialdehyde, and production of glutathione peroxidase
