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Animals were monitored for clinical signs, and oropharyngeal swabs were performed daily to assess viral load in the upper respiratory tract

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These data suggest that oxidative stress-induced iron overload is mainly originated intracellularly through HO-1 mediated iron release

In the Phase III NefIgArd trial, patients treated with Tarpeyo saw significantly better kidney function, as measured by the estimated glomerular filtration rate (eGFR) versus placebo after nine months on the drug and 15 months of follow-up

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