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[182] classified AKR inhibitors of plant origin into different groups based on their chemical structure, which include flavonoids, tannins, alkaloids, terpenoids, coumarins, and miscellaneous compounds

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MAPK/ERK pathway drives cell proliferation and differentiation

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M.DaskalakiE.ChidlowG.ZhangC.et al

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Tc dng v cch dng an ton 2

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Figure 4 8 Translational outlook: analogs, safety liabilities, and delivery strategies Erastin has demonstrated antitumor activity in several malignancies, including gastric and colorectal cancer (69, 70), and the inflammatory, iron-loaded, oxidative microenvironment shared by many tumors and EMS provides a coherent theoretical basis for applying this strategy to EMS (71, 72)

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The semaglutide pen used in weight management is a well-known example

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