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L-carnitine also blocks dietary vitamin B deficiency-induced left ventricular dysfunction and attenuates the diet-caused increase in serum BNP [23]
Reuter SE, Evans AM
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Mechanistically, TMAO may contribute to kidney disease pathogenesis by inhibiting autophagy, activating the NLRP3 inflammasome, and inducing mitochondrial dysfunction
Other findings demonstrate that eNOS activity remains unchanged in the aorta of rats treated with TMAO and in HAEC pre-incubated with 1 M of TMAO [57]
