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The defects arise from failure of the embryonic neural tube to close, which occurs between the 21st and 28th days after conception, a time when most women are unaware of their pregnancy (57)

Indices of insulin resistance (e.g., HOMA-IR, ADIPO-IR), low-grade systemic inflammation, and adipokine profiles co-vary with menstrual phase and partly mediate lipid fluctuations [96]

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This can result in a bad reaction or cause some drugs to be less effective

These reactions are initiated by the antibodies immunoglobulin G (IgG) and immunoglobulin M (IgM)

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