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In the study, half the participants lost 15% of their body weight while on a compounded GLP-1

Moreover, GLP-1 production has been shown in some neurons of the nucleus of the solitary tract (NTS) in the brain stem [for a review, see Holst (2007)]
Ecnoglutide also demonstrated superior waist circumference reduction

So when youre taking a GLP 1, youre getting a much higher longer lasting version of what your body produces, and it has to reach the brain through the gut brain barrier

Effects of semaglutide-loaded lipid nanocapsules on metabolic dysfunction-associated steatotic liver disease

The findings to date have been reassuring
