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If oral GLP-1s are priced too far out of reach, many people simply will not benefit from them
therefore, no dose adjustment is required when co-administered with semaglutide

In the last 10 to 15 years, discoveries on certain gut peptides that influence insulin secretion related to meal ingestion, namely incretins, have opened up a new paradigm in the treatment of diabetes [4]

It is important to understand that mild, transient bowel changes are a recognised pharmacological effect seen across the GLP-1 receptor agonist class
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