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Further support for BPC 157/serotonin relation is the inhibited release of enteric serotonin and inhibited intestinal motility, the increased survival rate of cultured enteric neurons, and the increased proliferation of cultured enteric glial cells (EGCs) by BPC 157 application [119]

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Doses greatly exceeding the nutritional requirements (for example, hundreds of milligrams daily) have not been studied in randomized trials for safety, so one should avoid mega doses in pregnancy unless treating a specific condition (such as pyridoxine-responsive seizures) under careful supervision